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Revisiting amino acids and peptides as anti-glycation agents. MedChemComm , 9 4 , Xenopus GLPinspired discovery of novel GLP-1 receptor agonists as long-acting hypoglycemic and insulinotropic agents with significant therapeutic potential. Biochemical Pharmacology , , Dominic N. McBrayer, Yftah Tal-Gan. Drug Development Research , 78 6 , Structural confirmation, single X-ray crystallographic behavior, molecular docking and other physico-chemical properties of gerberinol, a natural dimethyl dicoumarol from Gerbera lanuginosa Benth.

Journal of Molecular Structure , , Design, synthesis and biological evaluation of PEGylated Xenopus glucagon-like peptide-1 derivatives as long-acting hypoglycemic agents. Acta Biomaterialia , 51 , A rapid albumin-binding 5-fluorouracil prodrug with a prolonged circulation time and enhanced antitumor activity. Biomaterials Science , 5 3 , Pedersen, Knud J. ChemMedChem , 11 22 , Characterization of liraglutide, a glucagon-like peptide-1 GLP-1 receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease.

Design, Synthesis and Structure of Peptides and Proteins publications | IRB Barcelona

Brain Research , , Polymer Reviews , 56 3 , Site-specific fatty chain-modified exenatide analogs with balanced glucoregulatory activity and prolonged in vivo activity. Towards the next generation of biomedicines by site-selective conjugation. Chemical Society Reviews , 45 6 , Glucagon-like peptide-1 loaded phospholipid micelles for the treatment of type 2 diabetes: improved pharmacokinetic behaviours and prolonged glucose-lowering effects. RSC Advances , 6 97 , Protein—polymer conjugates prepared via host—guest interactions: effects of the conjugation site, polymer type and molecular weight on protein activity.


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Polymer Chemistry , 7 32 , Ahmed A. Al-Amiery, Yasameen K. Sign in via your Institution Sign in. Purchase Subscription prices and ordering Short-term Access To purchase short term access, please sign in to your Oxford Academic account above. This article is also available for rental through DeepDyve.

Design, synthesis and biological evaluation of immunostimulating mannosylated desmuramyl peptides

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"Synthesis, Kinetics & Biological Activity of Hetero cyclic Hydroxamic Acids" - Dr Vinita Rajeev

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A number of cyclic peptides are known to possess antibiotic activity and increased biological stability. Here we report the design, synthesis, and biological activity of a cyclic peptide 2 , which inhibits transcriptional activation by Tat protein in human cells with an IC50 of approximately 40 nM.

Cyclic peptides that can target specific RNA structures provide a new class of small molecules that can be used to control cellular processes involving RNA-protein interactions in vivo.

Design, Synthesis and Structure of Peptides and Proteins publications

Read Article at publisher's site. How does Europe PMC derive its citations network? Protein Interactions.