Revisiting amino acids and peptides as anti-glycation agents. MedChemComm , 9 4 , Xenopus GLPinspired discovery of novel GLP-1 receptor agonists as long-acting hypoglycemic and insulinotropic agents with significant therapeutic potential. Biochemical Pharmacology , , Dominic N. McBrayer, Yftah Tal-Gan. Drug Development Research , 78 6 , Structural confirmation, single X-ray crystallographic behavior, molecular docking and other physico-chemical properties of gerberinol, a natural dimethyl dicoumarol from Gerbera lanuginosa Benth.
Journal of Molecular Structure , , Design, synthesis and biological evaluation of PEGylated Xenopus glucagon-like peptide-1 derivatives as long-acting hypoglycemic agents. Acta Biomaterialia , 51 , A rapid albumin-binding 5-fluorouracil prodrug with a prolonged circulation time and enhanced antitumor activity. Biomaterials Science , 5 3 , Pedersen, Knud J. ChemMedChem , 11 22 , Characterization of liraglutide, a glucagon-like peptide-1 GLP-1 receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease.
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Brain Research , , Polymer Reviews , 56 3 , Site-specific fatty chain-modified exenatide analogs with balanced glucoregulatory activity and prolonged in vivo activity. Towards the next generation of biomedicines by site-selective conjugation. Chemical Society Reviews , 45 6 , Glucagon-like peptide-1 loaded phospholipid micelles for the treatment of type 2 diabetes: improved pharmacokinetic behaviours and prolonged glucose-lowering effects. RSC Advances , 6 97 , Protein—polymer conjugates prepared via host—guest interactions: effects of the conjugation site, polymer type and molecular weight on protein activity.
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Design, synthesis and biological evaluation of immunostimulating mannosylated desmuramyl peptides
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A number of cyclic peptides are known to possess antibiotic activity and increased biological stability. Here we report the design, synthesis, and biological activity of a cyclic peptide 2 , which inhibits transcriptional activation by Tat protein in human cells with an IC50 of approximately 40 nM.
Cyclic peptides that can target specific RNA structures provide a new class of small molecules that can be used to control cellular processes involving RNA-protein interactions in vivo.
Design, Synthesis and Structure of Peptides and Proteins publications
Read Article at publisher's site. How does Europe PMC derive its citations network? Protein Interactions.